Category Project Title Research Period Government Dept
Material Component Technology Development Development of Ultrasound Core Modules and Treatment Devices Utilizing Eco-Friendly Pb-Free Piezoelectric Materials Jul 2023 ~ Dec 2027 Ministry of Trade, Industry and Energy
Industrial Technology Innovation Development of Ultrasound-Mediated Drug Delivery Technology for the treatment of intractable cancer Jun 2022~Dec 2024 Ministry of Trade, Industry and Energy
Medical device usability support project Development of topical transporter(DDS) for anti-cancer drug Apr 2021 ~ Oct 2021 SeongNam Industry Promotion Agency
Government-led medical devices R&D project Development and Leading Commercialization of an USgHIFU for Intergrated Treatment with an AntiCancer Drug for Pancreatic Tumor Sep 2020 ~ Dec 2024 Korea Medical Device Development Fund
Bio-Health Custom Assignments Analysis and promotion of the effects of ultrasound-sensitive drug delivery system technology Jul 2020 ~ Sep 2020 SeongNam Industry Promotion Agency
Research manpower support project Project to support the recruitment of new research personnel Jun 2020 ~ May 2023 Korea Industrial Technology Association all rights reserved
KIURI Program K-BIO New Growth Engine KIURI Human Resources Training Center May, 2020 ~ Oct, 2023 Ministry of Science and ICT
Healthcare technology R&D project Development of novel brain tumor treatment by the penetration of blood-brain barrier with US-sensitizing nanomedicine complex Apr 2019 ~ Dec 2020 KHIDI
Gyeonggido Technology Development Development of image-guided drug delivery technology of nanocomposite containing ultrasound-sensitive anticancer drug for breast cancer treatment Oct 2017 ~ Sep 2018 Gyeonggido Business & Science Accelerator
TIPS Program Global Expansion Support Image-guided therapeutic agent delivery system using ultrasound contrast agent complex Sep 2017 ~ Sep 2018 MSS
Advanced Medical Technology Development Development of a chemotherapeutic agent encapsulating nanoparticle-microbubble nanocomplex for ultrasound guided hepatocellular carcinoma therapy using hepatic artery embolization Nov 2015 ~ Jun 2019 KHIDI
Medi-Bio Cluster R&BD Planning Support Technology & market research and licensing strategy establishment for convergence therapy of FUS and microbubble complex for treatment of pancreatic cancer and breast cancer Jun 2016 ~ Aug 2016 SeongNam Industry Promotion Agency
TIPS Program Image-guided therapeutic agent delivery system
using ultrasound contrast agent complex
Oct 2015 ~ Sep 2017 MSS


Sep 2023 [Scientific reports]
"Drug delivery by sonosensitive liposome and microbubble with acoustic‑lens attached ultrasound an in vivo feasibility study in a murine melanoma model"
Aug 2022 [Biomaterials Advances]
"Enhanced delivery to brain using sonosensitive liposome and microbubble with focused ultrasound"
Jul 2022 [Pharmaceutics]
"Effects of Lipid Shape and Interactions on the Conformation, Dynamics, and Curvature of Ultrasound-Responsive Liposomes"
Jun 2022 [Pharmaceutics]
"Ultrasound-Responsive Liposomes for Targeted Drug Delivery Combined with Focused Ultrasound"
Sep 2021 [Pharmaceuticals]
"PMP(Porphyrin-Micelle-PSMA) nanoparticles for photoacoustic and ultrasound signal amplification in Mouse Prostate Cancer Xenografts"
May 2021 [Ultrasonography]
"Early response evaluation of doxorubicin-nanoparticle-microbubble therapy in orthotopic hepatocellular carcinoma rat model using contrast-enhanced ultrasound and intravoxel incohernet motion-diffusion MRI"
Jan 2021 [Pharmaceuticals]
"PD-L1 Targeting Immune-Microbubble Complex Enhances Therapeutic Index in Murine Colon Cancer Models"
Jan 2021 [Theranostics]
"Development and evaluation of an ultrasound-triggered microbubble combined transarterial chemoembolization (TACE) formulation on rabbit VX2 liver cancer model"
Sep 2020 [Pharmaceuticals (Basel)]
Combination Therapy with Doxorubicine-Loaded Reduced Albumin Nanoparticles and Focused Ultrasound in Mouse Breast Cancer Xenografts
Nov 2020 [Ultrasound Med Biol]
Synergistic Effects of Pulsed Focused Ultrasound and a Doxorubicin-loaded Microparticle-Microbubble Complex in a Pancreatic Cancer Xenograft Mouse Model
May 2020 [materials (basel)]
Antitumor Efficacy of Focused Ultrasound-MFL Nanoparticles Combination Therapy in Mouse Breast Cancer Xenografts
In vitro Evaluation of Carbon‐Based Nanospheres as Drug Delivery Vesicles in Breast Cancer Cell
Mar 2020 [International Society for Magnetic Resonance in Medicine]
An Ultrasound-Responsive Dual-Modal US/T1-MRI Contrast Agent for Potential Diagnosis of Prostate Cancer
Feb 2020 [Int J Nanomedicine]
"Ultrasound-sensitizing nanoparticle complex for overcoming the blood-brain barrier: an effective drug delivery system"
Jan 2020 [cancers]
Antitumor Effects of Intra-Arterial Delivery of Albumin-Doxorubicin Nanoparticle Conjugated Microbubbles Combined with Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors
Dec 2019 [The Korea Society of Medical and Biological Engineering]
Effects of Anticancer Drug Delivery based on Microbubble and Microbubble-Nanoparticle Complex using Low-Intensity Focused Ultrasound in Breast Cancer Animal Model. Journal of Biomedical Engineering Research